Production of Anti-Endomysial Antibodies in Cultured Duodenal Mucosa: Usefulness in Coeliac Disease Diagnosis
نویسندگان
چکیده
منابع مشابه
Endomysial antibody in the diagnosis and management of coeliac disease.
This review determines the significance, usefulness, and application of the endomysial antibody test for coeliac disease in clinical practice.
متن کاملCOELIAC DISEASE Missing endomysial and reticulin binding of coeliac antibodies in transglutaminase 2 knockout tissues
Background: Autoantibodies against transglutaminase 2 (TG2) are thought to be responsible for the endomysial (EMA), reticulin (ARA), and jejunal antibody (JEA) tissue binding of serum samples from coeliac patients but the exclusive role of TG2 in these staining patterns has not yet been established. Aims: To evaluate whether antigens other than TG2 contribute to EMA/ARA/JEA reactions. Patients:...
متن کاملComparison of assays for anti-endomysial and anti-transglutaminase antibodies for diagnosis of pediatric celiac disease.
BACKGROUND Anti-endomysial antibodies are sensitive and specific markers for celiac disease. This antibody has recently been identified as an antibody to tissue transglutaminase, an enzyme that cross-links and stabilizes extracellular matrix proteins. OBJECTIVES To evaluate the clinical usefulness of an enzyme-linked immunoassay for anti-transglutaminase antibodies, and to compare the results...
متن کاملAnti-Endomysial and Anti-Tissue Transglutaminase Serological Test Compared with Small Bowel Biopsy in the Diagnosis of Celiac Disease
Abstract Background and Objective: Celiac is an autoimmune disease that is characterized by an immune-system-related damage in the intestinal tissue after consumption of gluten. There is not any general agreement for gold standard. The Purpose of this study was the evaluation of specificity and sensitivity of anti-endomysial (EMA) and anti-tissue transglutaminase (TTG) serological test compa...
متن کاملAbnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease Running head: TSLP in coeliac disease
From: First Department of Internal Medicine and Department of Molecular Medicine, St Matteo Hospital, University of Pavia, Pavia, Italy; Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, London, UK; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy; Faculty of Medicine, University of Southampton, Southampton, UK; Department of Gastr...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Gastroenterology
سال: 2002
ISSN: 0036-5521,1502-7708
DOI: 10.1080/003655202753387329